checkToP® INFO

PRINCIPLE

  • checkToP® is a urinary test which indicates the outcome of the treatment after a previously confirmed Termination of intrauterine Pregnancy (ToP).1
  • checkToP® is not a classical pregnancy test. checkToP® is designed to detect urinary hCG at concentrations ≥ 1 000 mIU/mL, the appropriate sensitivity level for a MToP follow-up test.1 This makes urine testing a well suited tool for MToP follow-up.
  • checkToP® is based on the human chorionic gonadotropin (hCG) blood testing. Indeed, it has been shown that measuring serum ß-hCG is as effective as ultrasound to confirm a successful medically induced abortion in early pregnancy (n=133).2 Moreover, the concentration of hCG and ß-hCG in urine are similar to or slightly higher than those of serum.3 Tests with detection limits of 1 000 mIU hCG/mL or higher are usually negative 2 weeks following complete induced abortion.4
  • ß-hCG levels drop rapidly under 1 000 IU/L after abortion.5

 

checkToP® is a complementary method to check medical abortion and do not replace the mandatory follow-up visit.

PROCEDURE

It has to be performed 14 days after the first MToP drug intake1

checkToP® must be performed on the first morning urine that should be more concentrated1

As simple as a pregnancy test

1

Hold the absorbant tip directly in
your urine stream or collect your urine 
in a clean and dry container and
dip the absorbent tip into the urine for
at least 5 to 10 seconds.
Take care no urine enters
in the test window
1

2

Lay the test device on a dry flat surface with the two windows facing up1

3

Wait between 5 to 10 minutes
to read the test results1

IMPORTANT

Do not read before 5 minutes
or after 10 minutes1

MToP: Medical Termination of Pregnancy

  1. checkToP® Instruction For Use.
  2. Behnamfar F et al. Misoprostol abortion: Ultrasonography versus Beta-hCG testing for verification of effectiveness. Pak J Med Sci 2013;29:1367-70.
  3. Stenman UH et al. The classification, functions and clinical use of different isoforms of HCG. Human Reprod Update 2006;12:769-84.
  4. Van der Lugt B et al. The disappearance of human chorionic gonadotropin from plasma and urine following induced abortion.
    Acta Obstet Gynecol Scand 1985;64:547-52.
  5. Steier JA et al. Human chorionic gonadotropin in maternal plasma after induced abortion, spontaneous abortion, and removed ectopic pregnancy. Obstet Gynecol 1984;64:391-4.

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